What is IBS Disease and its Cure

What helps with irritable bowel syndrome - and what doesn't?

Acosta RD, Cash BD. Clinical effects of colonic cleansing for general health promotion: a systematic review. Am J Gastroenterol 2009; 104 (11): 2830-2836; quiz 2837.

Alammar N, Wang L, Saberi B, Nanavati J, Holtmann G, Shinohara RT et al. The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data. BMC Complement Altern Med 2019; 19 (1): 21.

Altobelli E, Del Negro V, Angeletti PM, Latella G. Low-FODMAP Diet Improves Irritable Bowel Syndrome Symptoms: A Meta-Analysis. Nutrients 2017; 9 (9): 26.

Connell M, Shin A, James-Stevenson T, Xu H, Imperiale TF, Herron J. Systematic review and meta-analysis: Efficacy of patented probiotic, VSL # 3, in irritable bowel syndrome. Neurogastroenterol Motil 2018; 30 (12): e13427.

Dionne J, Ford AC, Yuan Y, Chey WD, Lacy BE, Saito YA et al. A Systematic Review and Meta-Analysis Evaluating the Efficacy of a Gluten-Free Diet and a Low FODMAPs Diet in Treating Symptoms of Irritable Bowel Syndrome. On J Gastroenterol 2018; 113 (9): 1290-1300.

Ernst E, Posadzki P, Lee MS. Reflexology: an update of a systematic review of randomized clinical trials. Maturitas 2011; 68 (2): 116-120.

Ford AC, Harris LA, Lacy BE, Quigley EM, Moayyedi P. Systematic review with meta-analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome. Aliment Pharmacol Ther 2018; 48 (10): 1044-1060.

Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR et al. Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis. On J Gastroenterol 2014; 109 (9): 1350-1365; quiz 1366.

Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR et al. Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. On J Gastroenterol 2014; 109 (10): 1547-1561; quiz 1546, 1562.

Ford AC, Vandvik PO. Irritable bowel syndrome: dietary interventions. BMJ Clin Evid 2015.

Khanna R, MacDonald JK, Levesque BG. Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysis. J Clin Gastroenterol 2014; 48 (6): 505-512.

Lasa JS, Altamirano MJ, Bracho LF, Paz S, Zubiaurre I. Efficacy and Safety of Intestinal Secretagogues for Chronic Constipation: A Systematic Review and Meta-Analysis. Arq Gastroenterol 2018; 55 (Suppl 1): 2-12.

Lee HH, Choi YY, Choi MG. The Efficacy of Hypnotherapy in the Treatment of Irritable Bowel Syndrome: A Systematic Review and Meta-analysis. J Neurogastroenterol Motil 2014; 20 (2): 152-162.

Manheimer E, Cheng K, Wieland LS, Min LS, Shen X, Berman BM et al. Acupuncture for Treatment of Irritable Bowel Syndrome. Cochrane Database Syst Rev 2012; (5): CD005111.

Menees SB, Maneerattannaporn M, Kim HM, Chey WD. The efficacy and safety of rifaximin for the irritable bowel syndrome: a systematic review and meta-analysis. On J Gastroenterol 2012; 107 (1): 28-35; quiz 36.

Moayyedi P, Ford AC, Talley NJ, Cremonini F, Foxx-Orenstein AE, Brandt LJ et al. The efficacy of probiotics in the treatment of irritable bowel syndrome: a systematic review. Good 2010; 59 (3): 325-332.

Moayyedi P, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR et al. The effect of fiber supplementation on irritable bowel syndrome: a systematic review and meta-analysis. On J Gastroenterol 2014; 109 (9): 1367-1374.

National Institute for Health and Clinical Excellence (NICE). Clinical practice guideline - Irritable bowel syndrome in adults: diagnosis and management. 04.2017. (NICE Clinical Guidelines; Volume 61).

Ockenga J. Nutrition (e.g. FODMAP diet *) in the treatment of irritable bowel syndrome. AVP 2016; 43 (3): 120-126.

Ruepert L, Quartero AO, de Wit NJ, van der Heijden GJ, Rubin G, Muris JW. Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome. Cochrane Database Syst Rev 2011; (8): CD003460.

Shah ED, Kim HM, Schoenfeld P. Efficacy and Tolerability of Guanylate Cyclase-C Agonists for Irritable Bowel Syndrome with Constipation and Chronic Idiopathic Constipation: A Systematic Review and Meta-Analysis. On J Gastroenterol 2018; 113 (3): 329-338.

IQWiG health information is intended to help understand the advantages and disadvantages of important treatment options and health care offers.

Whether one of the options we have described actually makes sense in individual cases can be clarified in a conversation with a doctor. Gesundheitsinformation.de can support the conversation with doctors and other experts, but not replace it. We do not offer individual advice.

Our information is based on the results of high quality studies. They are created by a team of authors from medicine, science and the editorial team and reviewed by experts outside of IQWiG. We describe in detail in our methods how we develop our texts and keep them up to date.